INGREDIENTS

Each pill contains the equiv. to dry:

 

Honeysuckle, flower 117.2mg

Chinese Figwort, root 117.2mg

Dong Quai, root 58.6mg

Red Peony, root 58.6mg

Licorice, root 23.4mg

 

Store below 30°C

Contains 200 x 200mg pills.

AUSTL 511709

Manufactured In Australia.

 

Indications: nose, mouth, gums, skin, ears, anus or scratching until bleeding. Excludes cuts & abrasions.

Actions: clear the heat, cools the blood, stops bleeding.

Dosage: 12 - 15 pills 2 - 3 times per day as symptoms return. Take near food.

Children: 6 months an over 1 pill per year of age up to the age of 10 as directed above.

Treat more, not less. Treat sooner, rather than later.

 

Si Miao Yong An Tang – "Bleeding"

A classical Chinese herbal formula traditionally used to support healthy circulation, calm severe inflammation and assist conditions involving abnormal bleeding and damaged blood vessels

 

What is Si Miao Yong An Tang?

Bleeding has a purpose.

When we cut ourselves, bleeding is part of the body's natural repair process.

But bleeding that occurs without injury, or bleeding that persists longer than it should, is different.

Bleeding gums.

Blood in the stool.

Nosebleeds.

Ulcerated skin that bleeds easily.

Fragile blood vessels.

Poor wound healing.

These symptoms often indicate that the tissues themselves have become inflamed and damaged.

Traditional Chinese Medicine (TCM) recognised this pattern centuries ago.

Si Miao Yong An Tang (四妙勇安汤) is one of Chinese medicine's great formulas for restoring healthy circulation in severely inflamed tissues while helping resolve what TCM describes as Heat Toxin and Blood Stasis.

At Chiron Medical we call it "Bleeding", because unexplained bleeding from inflamed tissues is one of the strongest clinical clues that this remarkable formula may be appropriate.

Importantly, any unexplained bleeding should always be medically investigated. This formula is designed to complement appropriate medical care—not replace it.

 

A Formula with Nearly 700 Years of History

Si Miao Yong An Tang first appeared in Yan Fang Xin Bian (New Compilation of Tested Prescriptions) during the Ming Dynasty, around the 14th century.

It earned a reputation as one of Chinese medicine's premier formulas for treating severe inflammatory vascular disorders, ulceration and threatened tissue loss.

Its name is often translated as:

"Four-Marvellous Decoction for Brave Preservation of Life."

That dramatic name reflects the seriousness of the conditions for which it was traditionally prescribed.

 

Why We Call It "Bleeding"

Although the formula has many uses, one symptom repeatedly appears throughout its classical indications:

Damaged blood vessels.

Patients may experience:

• bleeding gums

• chronic ulceration

• blood-stained wound discharge

• inflamed varicose ulcers

• diabetic ulcers

• fragile skin

• inflamed haemorrhoids with bleeding

• chronic inflammatory lesions

In Chinese medicine, these presentations often reflect a combination of:

• Heat

• toxicity

• Blood Stasis

• vascular injury

Rather than simply trying to stop bleeding, Si Miao Yong An Tang aims to improve the health of the underlying tissues and blood vessels.

 

What Is It Traditionally Used For?

Traditionally, Si Miao Yong An Tang is prescribed for Heat Toxin with Blood Stasis affecting the blood vessels and soft tissues.

Vascular Disease

• chronic leg ulcers

• venous ulcers

• peripheral vascular disease

• diabetic foot ulcers

• severe cellulitis

• threatened tissue necrosis

Bleeding Conditions

• bleeding gums associated with inflammation

• ulcerated tissues that bleed easily

• inflamed haemorrhoids

• chronic inflammatory skin lesions

Soft Tissue Infection

• abscesses

• carbuncles

• infected ulcers

• severe inflammatory swelling

Modern Integrative Applications

Practitioners may consider modified versions for selected patients with:

• chronic vascular insufficiency

• diabetic microvascular disease

• inflammatory vascular disorders

• difficult-to-heal wounds

Always alongside appropriate medical management.

 

​

The Five Herbs That Make the Formula

 

Healthy blood vessels do more than carry blood—they deliver oxygen, remove waste and allow tissues to repair themselves. When inflammation persists, circulation slows, vessels become damaged and healing begins to fail.

Si Miao Yong An Tang was designed to interrupt this process. Some herbs cool the inflammation damaging the vessels, others restore healthy circulation, while the remainder nourish the tissues and support repair. Together they help create the conditions needed for damaged blood vessels to recover before irreversible injury occurs.

 

Jin Yin Hua (Honeysuckle Flower)

 

Traditional Role

Jin Yin Hua leads the prescription. Like firefighters arriving first at the scene, it rapidly clears Heat and Toxicity, reducing the intense inflammation threatening healthy tissue while creating a safer environment for healing to begin.

 

Biomedical Role

Jin Yin Hua has been extensively researched for its antibacterial, antiviral, anti-inflammatory and antioxidant properties. Studies also suggest immunomodulatory effects that may help regulate excessive inflammatory responses associated with vascular injury.

 

Xuan Shen (Scrophularia Root)

 

Traditional Role

Once the fire begins to settle, Xuan Shen cools what remains. It nourishes Yin while cooling the Blood, protecting tissues that have become overheated and preventing ongoing inflammation from consuming the body's reserves.

 

Biomedical Role

Research suggests Xuan Shen possesses anti-inflammatory, antioxidant and immunomodulatory properties together with potential vascular protective effects. Experimental studies indicate it may help reduce oxidative stress while supporting endothelial health.

 

Dang Gui (Chinese Angelica Root)

 

Traditional Role

Inflamed tissues cannot heal without healthy circulation. Dang Gui restores the flow of Blood, delivering nourishment to damaged vessels while encouraging repair without creating further stagnation.

 

Biomedical Role

Modern research demonstrates improved microcirculation, anti-inflammatory activity and support for endothelial function. Dang Gui has also been investigated for its role in tissue repair and healthy vascular physiology.

 

Chi Shao (Red Peony Root)

 

Traditional Role

Where Dang Gui restores healthy circulation, Chi Shao clears the congestion that blocks it. It cools the Blood, disperses Blood Stasis and helps reopen the small vessels where inflammation has slowed normal flow.

 

Biomedical Role

Chi Shao contains paeoniflorin and related compounds with demonstrated anti-inflammatory, antioxidant and microcirculatory effects. Research also suggests protection of vascular endothelial cells and modulation of inflammatory cytokines involved in chronic vascular disease.

 

Gan Cao (Liquorice Root)

 

Traditional Role

Every successful prescription needs balance. Gan Cao harmonises the actions of the other herbs, moderating their intensity while supporting the body's own healing processes and ensuring the formula works as a coordinated whole.

 

Biomedical Role

Liquorice possesses well-established anti-inflammatory, antioxidant and gastroprotective properties. Research also suggests immunomodulatory effects that complement the broader vascular and anti-inflammatory actions of the formula.

 

Why These Herbs Work Together

 

Si Miao Yong An Tang recognises that inflammation and poor circulation rarely exist independently. As blood vessels become inflamed, circulation slows. As circulation slows, tissues receive less oxygen, inflammation persists and healing becomes increasingly difficult.

​

The formula breaks this cycle from both directions. Jin Yin Hua and Xuan Shen extinguish the inflammatory process, while Dang Gui and Chi Shao restore healthy circulation through damaged vessels. Gan Cao harmonises the prescription, allowing these complementary actions to work together without overwhelming the body's normal repair mechanisms.

​

In Traditional Chinese Medicine, the formula clears Heat Toxicity, cools the Blood, invigorates circulation and restores healthy tissue. It is traditionally prescribed where severe inflammation threatens the integrity of blood vessels and surrounding tissues.

​

From a modern biomedical perspective, the herbal constituents have demonstrated anti-inflammatory, antioxidant, antimicrobial and microcirculatory effects together with actions that support endothelial function, immune regulation and tissue repair. These complementary mechanisms align closely with current understanding that chronic vascular disease is driven by the combined effects of persistent inflammation, endothelial dysfunction and impaired tissue perfusion.

​

​

What Does Modern Research Say?

 

Si Miao Yong An Tang has attracted increasing research interest in:

 

Vascular Disease

• peripheral arterial disease

• diabetic foot ulcers

• chronic venous insufficiency

• vascular inflammation

 

Cardiovascular Disease

Research suggests possible effects on:

• endothelial function

• microvascular circulation

• inflammatory cytokines

• oxidative stress

 

Chronic Wound Healing

Experimental studies demonstrate:

• improved angiogenesis

• collagen remodelling

• reduced inflammatory signalling

• accelerated tissue repair

 

Inflammatory Disease

Research has explored:

• immune regulation

• chronic inflammatory disorders

• oxidative injury

• fibrosis

Although much of the evidence remains preclinical or based on moderate-quality clinical trials, the findings align remarkably well with the formula's traditional indications.

 

Beyond Bleeding

​

Despite its Chiron Medical name, Si Miao Yong An Tang is not a haemostatic formula in the conventional sense.

Its purpose is not simply to stop blood loss.

​

Instead, it addresses one of the most important principles in medicine:

Healthy tissues bleed less because healthy tissues are healthier.

By reducing inflammation and improving circulation simultaneously, the formula helps create an environment where damaged tissues are better able to repair themselves.

 

For Traditional Chinese Medicine Practitioners

Classical Pattern

 

Heat Toxin with Blood Stasis

Typical presentation:

• ulceration

• redness

• swelling

• pain

• bleeding

• purple tissues

• chronic non-healing wounds

• red tongue

• rapid pulse

 

Formula Strategy

Si Miao Yong An Tang:

• Clears Heat.

• Resolves toxicity.

• Nourishes Blood.

• Invigorates circulation.

• Promotes tissue healing.

 

Common Clinical Modifications

Frequently adapted for:

• diabetic ulcers

• peripheral vascular disease

• cellulitis

• vasculitis

• chronic wounds

• pressure injuries

• severe inflammatory skin disease

 

For Medical Doctors

Proposed Biomedical Actions

 

Current pharmacological research suggests multiple interacting mechanisms including:

• endothelial protection

• inhibition of inflammatory cytokines

• reduction of oxidative stress

• promotion of angiogenesis

• modulation of immune responses

• improvement of microvascular circulation

• support for extracellular matrix remodelling

 

Major bioactive compounds include:

• chlorogenic acid

• ferulic acid

• harpagoside-like iridoids

• glycyrrhizin

• flavonoids

 

These influence pathways including:

• NF-κB

• VEGF

• TGF-β

• oxidative stress signalling

• inflammatory cytokine regulation

 

Potential Herb–Drug Considerations

 

Clinical monitoring is appropriate in patients taking:

• anticoagulants

• antiplatelet medications

• immunosuppressive therapies

• corticosteroids

• diabetic medications

 

Although the formula supports vascular healing, it should never delay urgent assessment of:

• gastrointestinal bleeding

• unexplained vaginal bleeding

• haemoptysis

• haematuria

• rapidly deteriorating vascular ulcers

• suspected arterial insufficiency

 

Healthy Blood Vessels, Healthy Healing

Every organ depends upon healthy blood vessels.

​

When inflammation damages those vessels, healing slows.

Tissues become fragile.

Blood breaks through the tissues.

Ulcers may develop.

Bleeding can occur.

​

Si Miao Yong An Tang reminds us that treating bleeding is often about treating the health of the tissue itself, not simply trying to stop blood loss.

That is why we call it "Bleeding."

​

The name immediately alerts patients to one of its most recognisable clinical presentations while opening the door to a deeper understanding of inflammation, vascular health and tissue repair.

 

Key Takeaways

​

• Si Miao Yong An Tang is a classical vascular formula traditionally prescribed for severe inflammatory disorders involving Heat Toxin and Blood Stasis.

• At Chiron Medical it is called "Bleeding" because unexplained bleeding from inflamed tissues is one of its most recognisable traditional indications.

• The formula supports healthy circulation, vascular repair and tissue healing while reducing inflammatory activity.

• Modern research suggests anti-inflammatory, endothelial protective, antioxidant and angiogenic actions that align with its traditional use in chronic wounds, diabetic ulcers and vascular inflammation.

• It should always be prescribed by a qualified practitioner and used alongside appropriate medical care. Any unexplained bleeding requires prompt medical assessment, as it may be a sign of a serious underlying condition.

​

​

Clinical Insights

​

Severe Inflammation and Deep Infection

Bleeding is designed for serious inflammatory conditions where infection and inflammation have penetrated beyond the skin's surface into deeper tissues.

Typical presentations include:

• severe bacterial skin infections

• cellulitis

• boils

• carbuncles

• abscesses

• ulceration

• infected wounds

• deep inflammatory swelling

• vascular inflammation

Rather than simply reducing inflammation, the formula supports healthy circulation through inflamed tissues while assisting the body's response to severe infection.

 

Severe Acne

When acne progresses beyond simple pimples to become:

• painful

• cystic

• deeply inflamed

• widespread

practitioners frequently combine:

• Pimples & Acne (An Chuang Ling)

• Fatty Liver Detox (Yin Chen Hao Tang)

• Liver Fire (Long Dan Xie Gan Tang)

This layered approach addresses local skin inflammation, metabolic Heat and deeper inflammatory drivers that contribute to severe acne.

​

Acute Urinary Tract Infection

When bladder infection becomes severe, with:

• burning urination

• fever

• marked inflammation

• recurrent infection

practitioners frequently combine according to the dominant presentation:

• Bye UTI (Ba Zheng San) — when Damp-Heat is primarily affecting the bladder.

• Sudden Diarrhoea (Huang Lian Jie Du Tang) — when severe Heat Toxin and systemic inflammatory features dominate.

This allows treatment to be matched to the depth and distribution of inflammation rather than treating every urinary infection identically.

 

Acute Dermatitis and Eczema

When eczema becomes:

• intensely inflamed

• hot

• swollen

• secondarily infected

practitioners commonly combine:

• Itch (Xiao Feng San)

• Liver Fire (Long Dan Xie Gan Tang)

This addresses both the inflammatory skin response and the excessive Heat driving the flare.

 

Carbuncles, Boils and Purulent Skin Infection

Once boils become:

• fluctuant

• filled with pus

• painful

• surrounded by marked inflammation

practitioners frequently combine:

• Sudden Diarrhoea (Huang Lian Jie Du Tang)

• Inflammation (Wu Wei Xiao Du Yin)

This reflects progression from early superficial inflammation towards deep bacterial infection with tissue destruction.

 

Erythema Nodosum

Where inflammation extends into the deeper layers of the skin with:

• painful red nodules

• tenderness

• systemic inflammatory symptoms

practitioners often combine:

• Sudden Diarrhoea (Huang Lian Jie Du Tang)

to provide additional support against severe inflammatory Heat affecting the skin and subcutaneous tissues.

 

Perianal Infection

Inflammatory conditions involving the perianal region, particularly with:

• swelling

• redness

• pain

• abscess formation

may benefit from combining:

• Liver Fire (Long Dan Xie Gan Tang)

to address the intense inflammatory Heat affecting the lower pelvic region.

 

Chronic Psoriasis

Long-standing psoriasis frequently involves more than skin inflammation alone.

Where plaques become:

• thick

• chronic

• painful

• recurrent

practitioners commonly combine:

• Sharp Stabbing Pain (Huo Luo Xiao Ling Dan)

• Clear the Way (Xue Fu Zhu Yu Tang)

• Itch (Xiao Feng San)

• Liver Fire (Long Dan Xie Gan Tang)

• Restore Healthy Circulation (Tao Hong Si Wu Tang)

The choice depends upon whether inflammation, itching, circulatory impairment or chronic Blood Stasis predominates.

 

Rheumatoid Arthritis

Rheumatoid arthritis is characterised by persistent immune-mediated inflammation affecting the joints.

When active inflammation is accompanied by:

• swollen joints

• stiffness

• reduced movement

• progressive joint damage

practitioners frequently combine:

• Small Joint Arthritis (Shu Jin Huo Xue Tang)

• Sharp Stabbing Pain (Huo Luo Xiao Ling Dan)

This supports joint mobility while improving circulation through chronically inflamed tissues.

 

Understanding the Chiron Medical Infection & Inflammation Network

One of the major strengths of the Chiron Formula Network is recognising that inflammation develops in predictable stages.

Colds, Shivers & Sniffles (Gui Zhi Tang)

Early immune activation.

↓

No.1 Flu, Fever, Virus & Infection (Yin Qiao San)

Early Heat develops.

↓

X Factor (Xiao Chai Hu Tang)

The immune response stalls at the pivot point between exterior and interior disease.

↓

Throat Infection (Yang Yin Qing Fei Tang)

Heat localises within the upper respiratory tract.

↓

Liver Fire (Long Dan Xie Gan Tang)

Inflammatory Heat begins affecting specific organs and tissues.

↓

Inflammation (Wu Wei Xiao Du Yin)

Heat Toxin becomes established, producing red, swollen and painful infections affecting the skin and soft tissues.

↓

Bleeding (Si Miao Yong An Tang)

Inflammation penetrates deeper into the tissues.

Blood vessels become involved.

Circulation becomes compromised.

The risk of tissue destruction increases.

↓

Break High Fever (Chuan Xin Lian Jie Du Tang)

Inflammation becomes widespread and systemic, with high fever and severe constitutional illness.

 

From Inflammation to Tissue Damage

Modern medicine recognises that inflammation is not inherently harmful—it is an essential part of immune defence. However, when inflammation becomes severe or prolonged, it begins to damage blood vessels, connective tissue and healthy cells alongside the infection it is attempting to control.

​

This is the stage where Bleeding becomes clinically important. Classical Chinese physicians observed that deep infections were often accompanied by impaired circulation, severe swelling and damage to surrounding tissues. Rather than focusing solely on eliminating pathogens, Si Miao Yong An Tang was designed to support healthy blood flow through inflamed tissues while helping resolve intense inflammatory processes.

​

Within the Chiron Medical Infection Network, Bleeding represents the transition from local inflammation to deep tissue disease. It reminds practitioners that successful treatment is no longer just about controlling infection—it is also about preserving healthy tissue, restoring circulation and limiting long-term damage. That makes it one of the most powerful formulas in the Chiron range for severe inflammatory and infective conditions.